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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6075 | Epothilone B | Patupilone,EPO 906 | Apoptosis , Microtubule Associated , Antibiotic , Antifungal |
Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi... | |||
T6864 | Ixabepilone | BMS 247550,Ixempra,Azaepothilone B,BMS 247550-1 | Apoptosis , Microtubule Associated |
Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell ... | |||
T73084 | BMS 310705 | 21-Aminoepothilone B | |
BMS 310705 (21-Aminoepothilone B), an Epothilone B analog, specifically targets malignancies including ovarian, renal, bladder, and lung carcinoma. It significantly induces apoptosis through the mitochondrial-mediated pa... | |||
T68860 | Iso-Fludelone | ||
Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules agai... |